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Chebulic acid

Chebulic acid

Item no.	TMO-TN1042-10mM
Manufacturer	TargetMol
CASRN	23725-05-5
Amount	1 mL x 10 mM (in DMSO)
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	98.00%
Citations	Koo Y C , Pyo M C , Nam M H , et al. Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway.[J]. Toxicology in Vitro, 2016, 34:8-15.
Smiles	OC(=O)C[C@@H]([C@@H]1[C@H](OC(=O)c2cc(O)c(O)c(O)c12)C(O)=O)C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	23725-05-5,ROS,VEGFR
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	356.24
Description	Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, exhibits potent antioxidant activity by breaking protein cross-links induced by advanced glycation end-products (AGEs) and inhibiting AGE formation. It may also counteract AGE-induced endothelial cell dysfunction, suggesting it as a potential intervention for diabetic vascular complications.
Pathways	Others
Bioactivity	Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs.It has effects against the progression of AGE-induced endothelial cell dysfunction, may constitute a promising intervention agent against diabetic vascular complications
Receptor	ROS; VEGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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TMO-TN1042-10mM-datasheet.pdf

TMO-TN1042-10mM-safety-datasheet.pdf