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4,5-Dimethoxycanthin-6-one

4,5-Dimethoxycanthin-6-one

Manufacturer	TargetMol
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	5mg
Item no.	TMO-TN3013-5mg
CASRN	18110-87-7
eClass 6.1	32169090
eClass 9.0	32169090
Available
Short Description	4, 5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae).4, 5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity.4, 5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity. Dimethoxycanthin-6-one is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 μM, Ki: 2.6 μM), and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase.4, 5-(4, 5-Dimethoxycanthin-6-one) is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae). 4, 5-Dimethoxycanthin-6-one has antimicrobial activity against Staphylococcus aureus and its drug-resistant strains.4, 5-Dimethoxycanthin-6-one is cytotoxic to the tumor cell lines U937 and HepG2.4, 5-Dimethoxycanthin-6-one is a cytotoxicity inhibitor (IC50 : Ki : 6 μM, Ki : 6 μM).
Shipping	cool pack
Storage	-20°
Target names or alias	Methylnigakinone
Molecular Weight	280, 28
Pathway	Metabolism\|\|\|Microbiology/Virology
Target	P450\|\|\|Antibacterial\|\|\|PDE

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TMO-TN3013-5mg-datasheet.pdf

TMO-TN3013-5mg-safety-datasheet.pdf