Src I1

Item no.	V0093-5mg
Manufacturer	InvivoChem LLC
CASRN	179248-59-0
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Neuroscience Neural Mitochondrial Function Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	179248-59-0
Available
Description	InvivoChem Cat #:V0093CAS #:179248-59-0 Purity >=98% Description: Src Inhibitor 1 (Src-I1) is a novel, potent and selective dual site inhibitor of Src tyrosine kinases with potential anticancer activity. It acts by competitively binding to both the ATP- and peptide-binding sites (IC50 = 44 nM for Src and 88nM for Lck, respectively). Src is a non-receptor tyrosine kinase that is deregulated in many types of cancer. Thus Src Inhibitor 1 (Src-I1) can be potentially used for cancer treatment. References: Biochem J. 2007 Dec 15; 408(3):297-315; Biochemistry. 2001 Jun 19; 40(24):7084-91.
Molecular Weight (MW)	373.41
Formula	C22H19N3O3
CAS No.	179248-59-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 6 mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	6, 7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine
Synonyms	Src I1; SrcI1; Src I-1
SMILES Code	Chemical Name: 6, 7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine InChi Key: DMWVGXGXHPOEPT-UHFFFAOYSA-N InChi Code: InChI=1S/C22H19N3O3/c1-26-20-12-18-19(13-21(20)27-2)23-14-24-22(18)25-15-8-10-17(11-9-15)28-16-6-4-3-5-7-16/h3-14H, 1-2H3, (H, 23, 24, 25) SMILES: COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC

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