wp1066

Item no.	V0339-5mg
Manufacturer	InvivoChem LLC
CASRN	857064-38-1
Amount	5 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Oncology By Cell Type Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	857064-38-1
Available
Description	InvivoChem Cat #:V0339CAS #:857064-38-1Purity >=98% Description: WP1066, an AG49 derivative, is a novel and potent inhibitor of Janus kinases-JAK2 and STAT3 with potential antitumor activity. It inhibits JAK2 and STAT3 with IC50s of 2.30 uM and 2.43 uM in HEL cells. It shows potent in vitro antiproliferative activity and high in vivo antitumor efficacy. Description: References: Clin Cancer Res. 2008 Feb 1; 14(3):788-96; Cancer Res. 2007 Dec 1; 67(23):11291-9; Br J Cancer. 2010 May 25; 102(11):1592-9. References:
Molecular Weight (MW)	356.22
Formula	C17H14BrN3O
CAS No.	857064-38-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 71 mg/mL (199.3 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES Code	O=C(N[CH](C1=CC=CC=C1)C)/C(C#N)=C/C2=NC(Br)=CC=C2
Synonyms	WP-1066; WP 1066; WP1066 Chemical Name: (S, E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide InChi Key: VFUAJMPDXIRPKO-LQELWAHVSA-N InChi Code: InChI=1S/C17H14BrN3O/c1-12(13-6-3-2-4-7-13)20-17(22)14(11-19)10-15-8-5-9-16(18)21-15/h2-10, 12H, 1H3, (H, 20, 22)/b14-10+/t12-/m0/s1 SMILES Code: O=C(N[CH](C1=CC=CC=C1)C)/C(C#N)=C/C2=NC(Br)=CC=C2

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 10/2/2025

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