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OF-1 (OF-1)

OF-1 (OF-1)

Item no.	V0420-5mg
Manufacturer	InvivoChem LLC
CASRN	919973-83-4
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	919973-83-4
Available
Description	InvivoChem Cat #:V0420CAS #:919973-83-4Purity >=98% Description: OF-1 (OF1; SGC-OF-1) is a potent and selective inhibitor of bromodomain and PHD finger containing protein 1 (BRPF1) with important biological activity. It inhibits BRPF1B and BRPF2 bromodomain with Kds of 100 nM and 500 nM, respectively. BRPF (BRomodomain and PHD Finger containing) protein family are scaffolding proteins that assembles MYST histone acetyltransferase complexes. MYST complexes play important role in DNA repair, recombination, replication and transcription activation. Description: References: http://www.thesgc.org/chemical-probes/OF-1 References:
Molecular Weight (MW)	440.31
Formula	C17H18BrN3O4S
CAS No.	919973-83-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 76 mg/mL (172.6 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 4-Bromo-N-(6-methoxy-1, 3-dimethyl-2-oxo-2, 3-dihydro-1H-benzoimidazol-5-yl)-2-methyl-benzenesulfonamide InChi Key: YUNQZQREIHWDQT-UHFFFAOYSA-N InChi Code: InChI=1S/C17H18BrN3O4S/c1-10-7-11(18)5-6-16(10)26(23, 24)19-12-8-13-14(9-15(12)25-4)21(3)17(22)20(13)2/h5-9, 19H, 1-4H3 SMILES Code: O=S(C1=CC=C(Br)C=C1C)(NC2=C(OC)C=C(N3C)C(N(C)C3=O)=C2)=O
Synonyms	OF-1; SGC OF 1; SGC OF1; SGC OF-1; SGCOF1; SGC-OF-1;

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Amount: 5 mg

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Delivery expected until 10/2/2025

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