wz8040

Item no.	V0566-25mg
Manufacturer	InvivoChem LLC
CASRN	1214265-57-2
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1214265-57-2
Available
Description	InvivoChem Cat #:V0566CAS #:1214265-57-2Purity >=98% Description: WZ8040 is a novel, potent, mutant-selective and covalent / irreversible EGFR(T790M) inhibitor with potential anticancer activity, it does not inhibit the phosphorylation of ERBB2 (T798I). Description: References: Nature. 2009 Dec 24; 462(7276):1070-4. References:
Molecular Weight (MW)	481.01
Formula	C24H25ClN6OS
CAS No.	1214265-57-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 96 mg/mL (199.6 mM)
	Water: < 1 mg/mL
	Ethanol: 3 mg/mL (6.2 mM)
Other info	Chemical Name: N-(3-((5-chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)thio)phenyl)acrylamide InChi Key: KIISCIGBPUVZBF-UHFFFAOYSA-N InChi Code: InChI=1S/C24H25ClN6OS/c1-3-22(32)27-18-5-4-6-20(15-18)33-23-21(25)16-26-24(29-23)28-17-7-9-19(10-8-17)31-13-11-30(2)12-14-31/h3-10, 15-16H, 1, 11-14H2, 2H3, (H, 27, 32)(H, 26, 28, 29) SMILES Code: C=CC(NC1=CC=CC(SC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)=C1)=O
Synonyms	WZ8040; WZ 8040; WZ8040;

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