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Vardenafil HCl Trihydrate

Vardenafil HCl Trihydrate

Item no.	V0781-100mg
Manufacturer	InvivoChem LLC
CASRN	330808-88-3
Amount	100 mg
Quantity options	1 g 250 mg 25 mg 2 g 500 mg 50 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	330808-88-3
Available
Description	InvivoChem Cat #:V0781CAS #:330808-88-3 Purity >=98% Description: Vardenafil HCl Trihydrate (formerly also known as BAY 38-9456, trade names Levitra; Staxyn; Vivanza) is an approved medication acting as a phosphodiesterase/PDE inhibitor with important biological activity. It inhibits PDE5 and PDE1 with IC50s of 0.7 and 180 nM, respectively. Vardenafil has been approved used for treating erectile dysfunction. Vardenafil (VAR) is synthetic, highly selective, and potent inhibitor of phosphodiesterase-5 which competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. It is clinically approved for treatment of erectile dysfunction in men, including diabetic and postprostatectomy patients. Description References: Int J Impot Res. 2001 Oct; 13(5):282-90; Neuroscience. 2002; 113(2):351-61. References Related CAS: 224785-90-4 (free base); 330808-88-3 (HCl trihydrate); 224789-15-5 (2HCl)
Molecular Weight (MW)	579.11
Formula	C23H32N6O4S.HCl.3H2O
CAS No.	330808-88-3 (HCl trihydrate);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 116 mg/mL (200.3 mM)
	Water: 116 mg/mL (200.3 mM)
	Ethanol: 20 mg/mL (34.53 mM)
Other info	Chemical Name: 2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propylimidazo[5, 1-f][1, 2, 4]triazin-4(1H)-one dihydrochloride trihydrate InChi Key: NEAUGLIJDBPHAY-UHFFFAOYSA-N SMILES Code: O=C1N=C(C2=CC(S(=O)(N3CCN(CC)CC3)=O)=CC=C2OCC)NN4C1=C(C)N=C4CCC.[H]Cl.[H]Cl.[H]O[H].[H]O[H].[H]O[H]
Synonyms	BAY38-9456; BAY 38-9456; BAY-38-9456; trade names: Levitra; Staxyn; Vivanza; Vardenafil hydrochloride trihydrate; Vardenafil HCl; Levitra; Staxyn; Vivanza

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Amount: 100 mg

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Delivery expected until 10/2/2025

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