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gsk3787

gsk3787

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	500mg
Item no.	V0830-500mg
CASRN	188591-46-0
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V0830CAS #:188591-46-0Purity >=98% Description: GSK3787 (GSK-3787; GSK 3787) is a novel, potent, selective and irreversible antagonist of PPARdelta (Peroxisome proliferator-activated receptor delta) with important biological activity. It inhibits PPARdelta with a pIC50 of 6.6, also exhibits good pharmacokinetic properties. Description: Peroxisome proliferator-activated receptor delta References: J Med Chem. 2010; 53(4):1857-61; Mol Pharmacol. 2010; 78(3):419-30; Chem Biol. 1997; 4(12):909-18. References:
Molecular Weight (MW)	392.78
Formula	C15H12ClF3N2O3S
CAS No.	188591-46-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 79 mg/mL (201.1 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	O=C(NCCS(=O)(C1=NC=C(C(F)(F)F)C=C1)=O)C2=CC=C(Cl)C=C2
Synonyms	GSK-3787; GSK 3787; GSK3787; 4-chloro-N-(2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)ethyl)benzamide InChi Key: JFUIMTGOQCQTPF-UHFFFAOYSA-N InChi Code: InChI=1S/C15H12ClF3N2O3S/c16-12-4-1-10(2-5-12)14(22)20-7-8-25(23, 24)13-6-3-11(9-21-13)15(17, 18)19/h1-6, 9H, 7-8H2, (H, 20, 22) SMILES Code: O=C(NCCS(=O)(C1=NC=C(C(F)(F)F)C=C1)=O)C2=CC=C(Cl)C=C2

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Amount: 500mg

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Delivery expected until 6/6/2024