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Gimeracil

Gimeracil

Item no.	V0866-250mg
Manufacturer	InvivoChem LLC
CASRN	103766-25-2
Amount	250 mg
Quantity options	100 mg 10 g 1 g 2 g 500 mg 50 mg 5 g
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	103766-25-2
Available
Description	InvivoChem Cat #:V0866CAS #:103766-25-2Purity >=98% Description: Gimeracil (chlorodihydroxypyridine; CDHP; Gimestat), a pyridine/pyridone analog and an approved anticancer drug, is a potent inhibitor of the dihydropyrimidine dehydrogenase (DPYD) enzyme with potential anti-neoplastic activity. It is used as an adjunct to or in combination with other anticancer therapeutics to increase the systemic concentrations and therapeutic effectiveness of other antineoplastic drugs. Gimeracil inhibits the early steps in homologous recombination for double strand breaks repair of DNA. Description: References: Oncol Rep. 2010 Nov; 24(5):1307-13; Cancer Sci. 2011 Sep; 102(9):1712-6 References:
Molecular Weight (MW)	145.54
Formula	C5H4ClNO2
CAS No.	103766-25-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 29 mg/mL (199.3 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 5-chloro-2-hydroxypyridin-4(1H)-one InChi Key: ZPLQIPFOCGIIHV-UHFFFAOYSA-N InChi Code: InChI=1S/C5H4ClNO2/c6-3-2-7-5(9)1-4(3)8/h1-2H, (H2, 7, 8, 9) SMILES Code: O=C1C=C(O)NC=C1Cl
Synonyms	Gimestat, chlorodihydroxypyridine; CDHP; Gimeracil

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Amount: 250 mg

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Delivery expected until 10/2/2025

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