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Dorzolamide HCl

Dorzolamide HCl

Item no.	V0893-25mg
Manufacturer	InvivoChem LLC
CASRN	130693-82-2
Amount	25 mg
Quantity options	100 mg 10 mg 1 g 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	130693-82-2
Available
Description	InvivoChem Cat #:V0893CAS #:130693-82-2Purity >=98% Description: Dorzolamide HCl (also known as MK-507; L-671152 HCl; L671152; MK507; trade name Trusopt), an anti-glaucoma agent and CAI (carbonic anhydrase inhibitors), is a water-soluble and potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively. Dorzolamide wa approved for use as an anti-glaucoma agent that is topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Description: References: J Ocul Pharmacol Ther. 1997 Feb; 13(1):23-30; Vet Ophthalmol. 2001 Mar; 4(1):61-7. References: Related CAS:120279-96-1 (free base)
Molecular Weight (MW)	360.9
Formula	C10H16N2O4S3.HCl
CAS No.	130693-82-2 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: 14 mg/mL (38.79 mM)
	Ethanol: < 1 mg/mL
Other Name	Chemical Name: (4S, 6S)-4-(ethylamino)-6-methyl-5, 6-dihydro-4H-thieno[2, 3-b]thiopyran-2-sulfonamide 7, 7-dioxide hydrochloride InChi Key: OSRUSFPMRGDLAG-QMGYSKNISA-N InChi Code: InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13, 14)10-7(8)5-9(17-10)19(11, 15)16; /h5-6, 8, 12H, 3-4H2, 1-2H3, (H2, 11, 15, 16); 1H/t6-, 8-; /m0./s1 SMILES Code: O=S(C(S1)=CC([CH](NCC)C[CH]2C)=C1S2(=O)=O)(N)=O.[H]Cl
Synonyms	Dorzolamide; MK-507 (L-671152) HCl; MK-507; L-671152; TRUSOPT; Dorzolamide HCI; Dorzolamide Hydrochloride; L 671152; L671152; MK 507; MK507

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Amount: 25 mg

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