« Back
Home /
Dorzolamide HCl

Dorzolamide HCl

Item no.	V0893-1g
Manufacturer	InvivoChem LLC
CASRN	130693-82-2
Amount	1 g
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0893CAS #:130693-82-2Purity >=98% Description: Dorzolamide HCl (also known as MK-507; L-671152 HCl; L671152; MK507; trade name Trusopt), an anti-glaucoma agent and CAI (carbonic anhydrase inhibitors), is a water-soluble and potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively. Dorzolamide wa approved for use as an anti-glaucoma agent that is topically applied in the form of eye drops. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. Description: References: J Ocul Pharmacol Ther. 1997 Feb; 13(1):23-30; Vet Ophthalmol. 2001 Mar; 4(1):61-7. References: Related CAS:120279-96-1 (free base)
Molecular Weight (MW)	360.9
Formula	C10H16N2O4S3.HCl
CAS No.	130693-82-2 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: 14 mg/mL (38.79 mM)
	Ethanol: < 1 mg/mL
Other Name	Chemical Name: (4S, 6S)-4-(ethylamino)-6-methyl-5, 6-dihydro-4H-thieno[2, 3-b]thiopyran-2-sulfonamide 7, 7-dioxide hydrochloride InChi Key: OSRUSFPMRGDLAG-QMGYSKNISA-N InChi Code: InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13, 14)10-7(8)5-9(17-10)19(11, 15)16; /h5-6, 8, 12H, 3-4H2, 1-2H3, (H2, 11, 15, 16); 1H/t6-, 8-; /m0./s1 SMILES Code: O=S(C(S1)=CC([CH](NCC)C[CH]2C)=C1S2(=O)=O)(N)=O.[H]Cl
Synonyms	Dorzolamide; MK-507 (L-671152) HCl; MK-507; L-671152; TRUSOPT; Dorzolamide HCI; Dorzolamide Hydrochloride; L 671152; L671152; MK 507; MK507

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 g

available

Delivery expected until 10/2/2025

Express Delivery: Save 14 days

Compare

Add to wishlist

Get an offer