Comparison

almotriptan-malate-las-31416

Item no. V1027-10mg
Manufacturer InvivoChem LLC
CASRN 181183-52-8
Amount 10 mg
Quantity options 100 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 181183-52-8
Available
Description
InvivoChem Cat #:V1027CAS #:181183-52-8 Purity >=98%

Description: Almotriptan Malate (formerly LAS31416; LAS-31416; Almogran; Amignul; Almotrex; Axert), the maleate salt of Almotriptan which is an approved anti-migraine drug, is a potent and selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist. It is a triptan drug developed by Almirall for the treatment of heavy migraine headache in adults. Almotriptan acts by binding to the receptor which leads to vasoconstriction of the cranial blood vessels and thus affects the redistribution of cranial blood flow. It significantly increases cerebral blood flow and reduces blood flow through extracerebral cranial vessels.

Description:

References: J Pharm Bioallied Sci. 2014 Oct; 6(4):267-77; J Pharm Biomed Anal. 2013 Jul-Aug; 81-82:160-7.

References:

Related CAS #: 181183-52-8(Almotriptan Malate); 154323-57-6 (free base)

Molecular Weight (MW)
469.55
Formula
C17H25N3O2S.C4H6O5
CAS No.
181183-52-8
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 94 mg/mL (200.2 mM)
Water: < 1 mg/mL
Ethanol: 53 mg/mL (112.9 mM)
Other info

Chemical Name: N, N-dimethyl-2-(5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethan-1-amine 2-hydroxysuccinate

InChi Key: QHATUKWEVNMHRY-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21, 22)20-8-3-4-9-20; 5-2(4(8)9)1-3(6)7/h5-6, 11-12, 18H, 3-4, 7-10, 13H2, 1-2H3; 2, 5H, 1H2, (H, 6, 7)(H, 8, 9)

SMILES Code: CN(CCC1=CNC2=C1C=C(CS(=O)N3CCCC3)=O)C=C2)C.O=C(O)C(O)CC(O)=O

Synonyms
LAS 31416; Almogran; Almotrex; LAS31416; LAS-31416; Amignul; Axert; Almotriptan Malate.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
available

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