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Description: AZD-8418 is a novel and potent mGlu2 receptor PAM (positive allosteric modulators) that attenuates nicotine-taking and nicotine-seeking behavior.
References: Li X, D'Souza MS, Niño AM, Doherty J, Cross A, Markou A. Attenuation of nicotine-taking and nicotine-seeking behavior by the mGlu2 receptor positive allosteric modulators AZD8418 and AZD8529 in rats. Psychopharmacology (Berl). 2016 May; 233(10):1801-14. doi: 10.1007/s00213-016-4220-2. Epub 2016 Feb 13. PubMed PMID: 26873083.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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