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plerixafor

plerixafor

Item no.	V1488-10mg
Manufacturer	InvivoChem LLC
CASRN	110078-46-1
Amount	10 mg
Quantity options	100 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	110078-46-1
Available
Description	InvivoChem Cat #:V1488CAS #:110078-46-1 Purity >=98% Description: Plerixafor (formerly known as SDZ-SID-791; JLK-169; SID-791; AMD3100, AMD-3100, JM-3100, JM 3100; trade name Mozobil), the so called 'hematopoeitic stem cell mobilizer', is a novel and potent chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with an IC50 of 44 nM and 5.7 nM in cell-free assays, respectively. Plerixafor is a bicyclam with hematopoietic stem cell-mobilizing activity and has been approved as an immunostimulant to mobilize hematopoietic stem cells in cancer patients into the bloodstream. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. Description: References: J Immunol. 2009 Sep 1; 183(5):3204-11; J Invest Dermatol. 2012 Mar; 132(3 Pt 1):711-20. References: Related CAS#: 155148-31-5 (HCl)
Molecular Weight (MW)	502.78
Formula	C28H54N8
CAS No.	110078-46-1(free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO:< 1 mg/mL
	Water: 3 mg/mL (5.96 mM)
	Ethanol: 100 mg/mL (198.9 mM)
Solubility (In vivo)	30% Propylene glycol, 5% Tween 80, 65% D5W: 30 mg/mL
Synonyms	JM-3100; AMD3100; AMD 3100; JM-3100; AMD-3100; SDZ-SID-791; JLK-169; SID-791; JM-2987; Plerixafor HCl; MOZOBIL.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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