CASIN

Item no.	V17607-5mg
Manufacturer	InvivoChem LLC
CASRN	425399-05-9
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	425399-05-9
Available
Description	InvivoChem Cat #:V17607CAS #:425399-05-9Purity >=98% Description: CASIN is a novel, potent and selective inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo. References: 1. FlorianMC et al. Cdc42 activity regulates hematopoietic stem cell aging andrejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30. 2. PetersonJR et al. Biochemical suppression of small-molecule inhibitors: astrategy to identify inhibitor targets and signaling pathway components.

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Amount: 5 mg

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Delivery expected until 10/2/2025

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