Comparison

CASIN

Item no. V17607-10mg
Manufacturer InvivoChem LLC
CASRN 425399-05-9
Amount 10 mg
Quantity options 100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V17607CAS #:425399-05-9Purity >=98%

Description: CASIN is a novel, potent and selective inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo.

References:

1. FlorianMC et al. Cdc42 activity regulates hematopoietic stem cell aging andrejuvenation. Cell Stem Cell, 2012 May 4, 10(5):520-30.

2. PetersonJR et al. Biochemical suppression of small-molecule inhibitors: astrategy to identify inhibitor targets and signaling pathway components.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
available

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