Comparison

Phosphoramidon disodium salt

Item no. V1913-5mg
Manufacturer InvivoChem LLC
CASRN 164204-38-0
Amount 5 mg
Quantity options 100 mg 10 mg 1 mg 250 mg 25 mg 500 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 164204-38-0
Available
Description
InvivoChem Cat #:V1913CAS #:164204-38-0 Purity >=98%

Description: Phosphoramidon disodium salt is a potent metalloendopeptidase inhibitor, which is widely used as a biochemical research tool. Phosphoramidon In porcine aortic endothelial cells, phosphoramidon (10-4 M) inhibited immunoreactive-endothelin (IR-ET) release by 10-20% and increased IR-CTF levels. These results suggested that phosphoramidon reduced the IR-ET release through affecting the conversion of big ET-1 to ET-l. In cultured endothelial cells, phosphoramidon inhibited the increase of ET-1 and C-terminal fragment (CTF) of big ET-1. However, phosphoramidon increased big ET-1 secretion

References: Biochem Biophys Res Commun. 1975; 65:352-7; Surg Endosc. 2001; 15:882-5; J Mol Neurosci. 2011; 43(3):424-7.

Molecular Weight (MW)
588.48
Formula
C23H34N3Na2O10P
CAS No.
164204-38-0
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (169.9 mM)
Water: 100 mg/mL (169.9 mM)
Ethanol: < 1 mg/mL
Other info

Chemical Name: sodium (oxido(((2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phosphoryl)-L-leucyl-L-tryptophanate

InChi Key: OQKHVXFOYFBMDJ-ODIUWQMJSA-L

InChi Code: InChI=1S/C23H34N3O10P.2Na/c1-11(2)8-16(26-37(33, 34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15; ; /h4-7, 10-12, 16-20, 23-24, 27-29H, 8-9H2, 1-3H3, (H, 25, 30)(H, 31, 32)(H2, 26, 33, 34); ; /q; 2*+1/p-2/t12-, 16-, 17-, 18-, 19+, 20+, 23-; ; /m0../s1

SMILES Code: O[CH]1[CH](C)O[CH](OP(N[CH](CC(C)C)C(N[CH](C(O[Na])=O)CC2=CNC3=CC=CC=C23)=O)(O[Na])=O)[CH](O)[CH]1O

Synonyms

Phosphoramidon sodium

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
available

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