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Phosphoramidon disodium salt

Phosphoramidon disodium salt

Item no.	V1913-250mg
Manufacturer	InvivoChem LLC
CASRN	164204-38-0
Amount	250 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1913CAS #:164204-38-0 Purity >=98% Description: Phosphoramidon disodium salt is a potent metalloendopeptidase inhibitor, which is widely used as a biochemical research tool. Phosphoramidon In porcine aortic endothelial cells, phosphoramidon (10-4 M) inhibited immunoreactive-endothelin (IR-ET) release by 10-20% and increased IR-CTF levels. These results suggested that phosphoramidon reduced the IR-ET release through affecting the conversion of big ET-1 to ET-l. In cultured endothelial cells, phosphoramidon inhibited the increase of ET-1 and C-terminal fragment (CTF) of big ET-1. However, phosphoramidon increased big ET-1 secretion References: Biochem Biophys Res Commun. 1975; 65:352-7; Surg Endosc. 2001; 15:882-5; J Mol Neurosci. 2011; 43(3):424-7.
Molecular Weight (MW)	588.48
Formula	C23H34N3Na2O10P
CAS No.	164204-38-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (169.9 mM)
	Water: 100 mg/mL (169.9 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: sodium (oxido(((2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phosphoryl)-L-leucyl-L-tryptophanate InChi Key: OQKHVXFOYFBMDJ-ODIUWQMJSA-L InChi Code: InChI=1S/C23H34N3O10P.2Na/c1-11(2)8-16(26-37(33, 34)36-23-20(29)19(28)18(27)12(3)35-23)21(30)25-17(22(31)32)9-13-10-24-15-7-5-4-6-14(13)15; ; /h4-7, 10-12, 16-20, 23-24, 27-29H, 8-9H2, 1-3H3, (H, 25, 30)(H, 31, 32)(H2, 26, 33, 34); ; /q; 2*+1/p-2/t12-, 16-, 17-, 18-, 19+, 20+, 23-; ; /m0../s1 SMILES Code: O[CH]1[CH](C)O[CH](OP(N[CH](CC(C)C)C(N[CH](C(O[Na])=O)CC2=CNC3=CC=CC=C23)=O)(O[Na])=O)[CH](O)[CH]1O
Synonyms	Phosphoramidon sodium

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Amount: 250 mg

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