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cyclobenzaprine-hcl

cyclobenzaprine-hcl

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	5g
Item no.	V1918-5g
CASRN	6202-23-9 (HCl);
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V1918CAS #:6202-23-9 (HCl); Purity >=98% Description: Cyclobenzaprine HCl (also known as MK130; Flexeril) is a potent muscle relaxant by blocking pain sensations, used as a medication for the treatment of skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Cyclobenzaprine strongly binds to 5-HT2 receptors with a Ki value of 62 nM. Cyclobenzaprine binds to 5-HT1 receptor with a Ki value of 2900 nM. In 16 of 21 spontaneously active neurons, the administration of cyclobenzaprine at 1 mg/kg decreased the discharge rate of neurons, while two neurons showed no response and three neurons demonstrated an increased rate. References: Eur J Pharmacol. 1996 Sep 5; 311(1):29-35; Eur J Pharmacol. 2003 Jan 1; 458(1-2):91-9. Related CAS#: 303-53-7 (free base); 6202-23-9 (HCl)
Molecular Weight (MW)	311.85
Formula	C20H22ClN
CAS No.	6202-23-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 62 mg/mL (198.8 mM)
	Water: 62 mg/mL (198.8 mM)
	Ethanol: N/A
Solubility (In vivo)	Chemical Name: (Z)-3-(10H-dibenzo[a, d][7]annulen-10-ylidene)-N, N-dimethylpropan-1-amine hydrochloride InChi Key: VJSLSIJWPIOMIP-XHFAFUTOSA-N InChi Code: InChI=1S/C20H21N.ClH/c1-21(2)13-7-11-19-15-17-9-4-3-8-16(17)14-18-10-5-6-12-20(18)19; /h3-6, 8-12, 14-15H, 7, 13H2, 1-2H3; 1H/b19-11-; SMILES Code: CN(C)CC/C=C1C2=CC=CC=C2C=C(C=CC=C3)C3=C\1.[H]Cl
Synonyms	MK-130 HCl; MK130 hydrochloride; MK 130; Flexeril; Proheptatriene; Lisseril; Proeptatriene; Proheptatrien

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Amount: 5g

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Delivery expected until 6/6/2024