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Description:Otenabant free base (also known as CP-945, 598) is a novel, potent and highlyselective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, itexhibits > 10, 000-fold greater selectivity against human CB2 receptor.Otenabant is a approved drug developed by Pfizer for the treatment ofobesity, but development for this drug has been discontinued due to theproblems seen during clinical use of the similar drug rimonabant.
References: J Med Chem. 2009 Jan 22; 52(2):234-7; Biochem Biophys Res Commun. 2010 Apr 2; 394(2):366-71.
Related CAS#: 686344-29-6 (free base); 86347-12-6 (HCl)
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