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PF-06446846 hydrochloride

PF-06446846 hydrochloride

Item no.	V27359-25mg
Manufacturer	InvivoChem LLC
CASRN	1632250-50-0
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V27359CAS #:1632250-50-0Purity >=98% Description: PF?06446846 is a novel, orally bioavailable and potent PCSK9inhibitor that inhibits translation of PCSK9 by inducing the ribosometo stall around codon, mediated by the sequence of the nascent chainwithin the exit tunnel. PF-06446846 reduces plasma PCSK9 and totalcholesterol levels in rats following oral dosing. PF-06446846 is highlyselective for the inhibition of PCSK9 translation. orally bioavailable References: PLoS Biol. 2017 Mar 21; 15(3):e2001882.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 12/4/2025

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