« Back
Home /
pf-06446846-hydrochloride

pf-06446846-hydrochloride

Item no.	V27359-5mg
Manufacturer	InvivoChem LLC
CASRN	1632250-50-0
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1632250-50-0
Available
Description	InvivoChem Cat #:V27359CAS #:1632250-50-0Purity >=98% Description: PF?06446846 is a novel, orally bioavailable and potent PCSK9inhibitor that inhibits translation of PCSK9 by inducing the ribosometo stall around codon, mediated by the sequence of the nascent chainwithin the exit tunnel. PF-06446846 reduces plasma PCSK9 and totalcholesterol levels in rats following oral dosing. PF-06446846 is highlyselective for the inhibition of PCSK9 translation. orally bioavailable References: PLoS Biol. 2017 Mar 21; 15(3):e2001882.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Delivery expected until 7/3/2025

Express Delivery: Save 17 days

Compare

Add to wishlist

Recommend by mail