Comparison

fd-in-1

Manufacturer InvivoChem LLC
Category
Type Biochemicals
Specific against other
Amount 100mg
Item no. V32394-100mg
CASRN 1646682-14-5
eClass 6.1 32160405
eClass 9.0 32160490
Available
Description
InvivoChem Cat #:V32394CAS #:1646682-14-5Purity >=98%

Description: FD-IN-1 is a novel and potent factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase beta2 with IC50s of 7.7 and 6.5uM, respectively.

References: Design, Synthesis, and Preclinical Characterization of Selective Factor DInhibitors Targeting the Alternative Complement Pathway. J Med Chem.2019 May 9; 62(9):4656-4668.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100mg
Available: In stock
available

Delivery expected until 6/6/2024 

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