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E4031 diHCl

E4031 diHCl

Item no.	V3382-5mg
Manufacturer	InvivoChem LLC
CASRN	113559-13-0
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	113558-89-7
Available
Description	InvivoChem Cat #:V3382CAS #:113559-13-0 (2HCl salt); 113558-89-7 (free base)Purity >=98% Description: E-4031 is a novel, potent and selective blocker of hERG K+ channels, which is also termed as a class III antiarrhythmic agent. It selectively blocks hERG potassium (K+) channels. E4031 inhibits the rapid delayed-rectifier K+ current (IKr) and reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na+ or Ca2+ inward currents. References: Br J Pharmacol. 2012 Jan; 165(2):467-78.; Eur J Pharmacol. 2014 Oct 5; 740:263-70.
	Name: E4031 HCl CAS#: 113559-13-0 (2HCl) Chemical Formula: C21H29Cl2N3O3S Exact Mass: 401.1773 Molecular Weight: 474.44 Elemental Analysis: C, 53.16; H, 6.16; Cl, 14.94; N, 8.86; O, 10.12; S, 6.76
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: E4031; E-4031; E 4031; E4031 2HCl; E4031 dihydrochloride Chemical Name: N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide dihydrochloride InChi Key: ZQBNWMFBOSOOLX-UHFFFAOYSA-N InChi Code: InChI=1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2, 26)27; ; /h3-9, 18, 23H, 10-15H2, 1-2H3; 2*1H SMILES Code: CS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O.[H]Cl.[H]Cl

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Amount: 5 mg

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Delivery expected until 12/4/2025

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