« Back
Home /
E4031 diHCl

E4031 diHCl

Item no.	V3382-10mg
Manufacturer	InvivoChem LLC
CASRN	113559-13-0
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3382CAS #:113559-13-0 (2HCl salt); 113558-89-7 (free base)Purity >=98% Description: E-4031 is a novel, potent and selective blocker of hERG K+ channels, which is also termed as a class III antiarrhythmic agent. It selectively blocks hERG potassium (K+) channels. E4031 inhibits the rapid delayed-rectifier K+ current (IKr) and reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na+ or Ca2+ inward currents. References: Br J Pharmacol. 2012 Jan; 165(2):467-78.; Eur J Pharmacol. 2014 Oct 5; 740:263-70.
	Name: E4031 HCl CAS#: 113559-13-0 (2HCl) Chemical Formula: C21H29Cl2N3O3S Exact Mass: 401.1773 Molecular Weight: 474.44 Elemental Analysis: C, 53.16; H, 6.16; Cl, 14.94; N, 8.86; O, 10.12; S, 6.76
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: E4031; E-4031; E 4031; E4031 2HCl; E4031 dihydrochloride Chemical Name: N-[4-[1-[2-(6-methylpyridin-2-yl)ethyl]piperidine-4-carbonyl]phenyl]methanesulfonamide dihydrochloride InChi Key: ZQBNWMFBOSOOLX-UHFFFAOYSA-N InChi Code: InChI=1S/C21H27N3O3S.2ClH/c1-16-4-3-5-19(22-16)12-15-24-13-10-18(11-14-24)21(25)17-6-8-20(9-7-17)23-28(2, 26)27; ; /h3-9, 18, 23H, 10-15H2, 1-2H3; 2*1H SMILES Code: CS(=O)(NC1=CC=C(C(C2CCN(CCC3=NC(C)=CC=C3)CC2)=O)C=C1)=O.[H]Cl.[H]Cl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10 mg

available

Delivery expected until 12/4/2025

Express Delivery: Save 17 days

Compare

Add to wishlist

Get an offer