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kb-nb77-78

kb-nb77-78

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	2mg
Item no.	V3423-2mg
CASRN	1350622-33-1
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V3423CAS #:1350622-33-1 Purity >=98% Description: kb-NB77-78 is a CID797718 analog but without PKD (Protein kinase D) inhibitory activity. Protein kinase D (PKD) belongs to a family of serine/threonine kinases that play an important role in basic cellular processes and are implicated in the pathogenesis of several diseases. Progress in our understanding of the biological functions of PKD has been limited due to the lack of a PKD-specific inhibitor. The benzoxoloazepinolone CID755673 was recently reported as the first potent and kinase-selective inhibitor for this enzyme. For structure-activity analysis purposes, a series of analogs was prepared and their in vitro inhibitory potency evaluated. References: Pharmaceutics. 2011; 3(2):186-228.
	Name: kb-NB77-78 CAS#: 1350622-33-1 Chemical Formula: C18H25NO3Si Exact Mass: 331.1604 Molecular Weight: 331.48 Elemental Analysis: C, 65.22; H, 7.60; N, 4.23; O, 14.48; Si, 8.47
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Kb-NB77-78; KbNB7778; Kb NB77 78 Chemical Name: 9-((tert-butyldimethylsilyl)oxy)-1, 2, 3, 4-tetrahydro-5H-chromeno[3, 4-b]pyridin-5-one InChi Key: UNMWMPXUIXEQJZ-UHFFFAOYSA-N InChi Code: InChI=1S/C18H25NO3Si/c1-18(2, 3)23(4, 5)22-12-8-9-15-14(11-12)13-7-6-10-19-16(13)17(20)21-15/h8-9, 11, 19H, 6-7, 10H2, 1-5H3 SMILES Code: O=C(C1=C2CCCN1)OC3=C2C=C(O[Si](C)(C(C)(C)C)C)C=C31

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Amount: 2mg

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Delivery expected until 6/6/2024