rg7834

Item no.	V3656-5mg
Manufacturer	InvivoChem LLC
CASRN	2072057-17-9
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2072057-17-9
Available
Description	InvivoChem Cat #:V3656CAS #:2072057-17-9 Purity >=98% Description: RG7834 S-isomer, also known as RO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production. RG7834 is highly selective for HBV, and has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues. RG7834 (also known as RO 7020322) is a novel, potent, highly selective and orally bioavailable HBV inhibitor which potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively in dHepaRG Cells. RG7834 is a novel oral HBV viral gene expression inhibitor that blocks viral antigen and virion production. RG7834 has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues. References: J Med Chem. 2018 Oct 4. Related CAS#: 2072057-17-9 (S-isomer); 2072057-18-0 (R-isomer); 199482-36-3 (S-isomer hydrate); 1802407-46-0 (racemic)
	Name: RG7834 CAS#: 2072057-18-0 (R-isomer); 2072057-17-9 (S-isomer); 199482-36-3 (S-isomer hydrate); 1802407-46-0 (racemic); Chemical Formula: C22H27NO6 Exact Mass: 401.1838 Molecular Weight: 401.46 Elemental Analysis: C, 65.82; H, 6.78; N, 3.49; O, 23.91
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: RO7020322; RO 7020322; RO-7020322; RG7834; RG 7834; RG-7834; Chemical Name: (6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6, 7-dihydrobenzo[a]quinolizine-3-carboxylic acid SMILES Code: O=C(C1=CN2[CH](C(C)C)CC3=CC(OCCCOC)=C(OC)C=C3C2=CC1=O)O

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Amount: 5mg

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