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TAS-301

TAS-301

Item no.	V4159-5mg
Manufacturer	InvivoChem LLC
CASRN	193620-69-8
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	193620-69-8
Available
Description	InvivoChem Cat #:V4159CAS #:193620-69-8Purity >=98% Description: TAS-301 is a novel, potent and selective inhibitor of smooth muscle cell migration and proliferation and inhibits intimal thickening after balloon injury to rat carotid arteries. TAS-103 inhibits smooth muscle cell migration and proliferation. It also inhibits intimal thickening after balloon injury to rat carotid arteries. TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor. TAS-103 inhibits calcium-dependent signal transduction and cytoskeletal reorganization. Description: References: J Pharmacol Exp Ther. 1998 Jun; 285(3):1280-6.; Jpn J Pharmacol. 2000 Nov; 84(3):252-8. References:
	Name: TAS-301 CAS#: 193620-69-8 Chemical Formula: C23H19NO3 Exact Mass: 357.13649 Molecular Weight: 357.41 Elemental Analysis: C, 77.29; H, 5.36; N, 3.92; O, 13.43
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: TAS-301, TAS301, TAS301 IUPAC/Chemical Name: 3-[Bis(4-methoxyphenyl)methylene]-1, 3-dihydro-2H-indol-2-one InChi Key: KUEYYIJXBRWZIB-UHFFFAOYSA-N InChi Code: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H, 1-2H3, (H, 24, 25) SMILES Code: O=C1NC2=C(C=CC=C2)/C1=C(C3=CC=C(OC)C=C3)\C4=CC=C(OC)C=C4

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Amount: 5 mg

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