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k-ras-g12c-in-2

k-ras-g12c-in-2

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	25mg
Item no.	V4788-25mg
CASRN	1629267-75-9
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V4788CAS #:1629267-75-9Purity >=98% Description: K-Ras G12C-IN-2 is a novel, potent and irreversible/covalent inhibitor of K-Ras protein with G12C mutation. The compound inhibits KRAS G12C which is a well-validated driver mutation present in approximately 14% of NSCLC adenocarcinoma patients and 5% of CRC patients. Patients with KRAS mutation-positives cancers generally have a poor prognosis and resistant to standard therapies. References: WO2014152588A1
	Molecular Weight: 418.92 Formula: C??H??ClN?O? CAS No.: 1629267-75-9 SMILES: ClC1=C(C2CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	K-Ras G12C-IN-2

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Amount: 25mg

available

Delivery expected until 6/6/2024