« Back
Home /
ci-1044

ci-1044

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	100mg
Item no.	V4821-100mg
CASRN	197894-84-1
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V4821CAS #:197894-84-1Purity >=98% Description: CI-1044 is a novel, potent and orally bioavailable PDE4 (phosphodiesterase 4) inhibitor with IC50s of 0.29, 0.08, 0.56, 0.09 uM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3, respectively. It inhibits LPS-induced TNF-alpha production in whole blood in chronic obstructive pulmonary disease (COPD) patients. References: Fundam Clin Pharmacol. 2010 Feb; 24(1):73-82.
	Name: CI-1044 CAS#: 197894-84-1 Chemical Formula: C23H19N5O2 Exact Mass: 397.15387 Molecular Weight: 397.43 Elemental Analysis: C, 69.51; H, 4.82; N, 17.62; O, 8.05
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: PD-189659; PD 189659; PD189659; CI-1044; CI 1044; CI1044; UNII-O4T475XIIY. IUPAC/Chemical Name: (R)-N-(9-amino-4-oxo-1-phenyl-3, 4, 6, 7-tetrahydro-[1, 4]diazepino[6, 7, 1-hi]indol-3-yl)nicotinamide InChi Key: XGXOSJSGDNPEEF-NRFANRHFSA-N InChi Code: InChI=1S/C23H19N5O2/c24-17-11-15-8-10-28-20(15)18(12-17)19(14-5-2-1-3-6-14)26-21(23(28)30)27-22(29)16-7-4-9-25-13-16/h1-7, 9, 11-13, 21H, 8, 10, 24H2, (H, 27, 29)/t21-/m0/s1 SMILES Code: Nc1cc2CCN3C(=O)[CH](NC(=O)c4cccnc4)N=C(c5ccccc5)c(c1)c23

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100mg

available

Delivery expected until 6/6/2024