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symadex

symadex

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	10mg
Item no.	V5115-10mg
CASRN	138154-39-9
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V5115CAS #:138154-39-9Purity >=98% Description: Symadex (formerly XLS-002, C-1311, and imidazoacridone) is a novel anticancer agent of the imidazoacridinone class which has been recommended for Phase II clinical trials a few years ago, it has shown activity in experimental tumour models both in vitro and in nude mice. C-1311 at the EC(99) dose delayed progression of cells through the S phase which was followed by G2 arrest. C-1311 does not induce rapid apoptosis in HT-29 cells, instead drug exposure leads to prolonged G2 arrest followed by G2 to M transit and cell death during mitosis in the process of mitotic catastrophe. References: J Pharmacol Exp Ther. 2013 Sep; 346(3):393-405. Related CAS #: 138154-39-9 (free base); 138154-55-9 (HCl)
	Name: Symadex free base CAS#: 138154-39-9 (free base) Chemical Formula: C20H22N4O2 Exact Mass: 350.17428 Molecular Weight: 350.422 Elemental Analysis: C, 68.55; H, 6.33; N, 15.99; O, 9.13
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: imidazoacridone; C-1311, C1311; C 1311; XLS-002; XLS 002; XLS002; Imidacrine; SYMADEX. Chemical Name: 5-((2-(diethylamino)ethyl)amino)-8-hydroxy-6H-imidazo[4, 5, 1-de]acridin-6-one InChi Key: CUNDRHORZHFPLY-UHFFFAOYSA-N InChi Code: InChI=1S/C20H22N4O2/c1-3-23(4-2)10-9-21-15-6-7-16-19-18(15)20(26)14-11-13(25)5-8-17(14)24(19)12-22-16/h5-8, 11-12, 21, 25H, 3-4, 9-10H2, 1-2H3 SMILES Code: O=C1C2=C(C=CC(O)=C2)N(C=N3)C4=C3C=CC(NCCN(CC)CC)=C14

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Amount: 10mg

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Delivery expected until 6/6/2024