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indotecan

indotecan

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	50mg
Item no.	V5157-50mg
CASRN	915303-09-2
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V5157CAS #:915303-09-2Purity >=98% Description: Indotecan (LMP400; NSC724998) is a novel, potent and selective topoisomerase I inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. It has potential anticancer activitity and is currently in Phase I trials. Human nuclear type IB topoisomerase (Top1) inhibitors are widely used and powerful anticancer agents. I References: Mol Cancer Ther. 2015 Nov; 14(11):2552-9. Related CAS #: 915303-09-2 (Indotecan; LMP-400); 915360-05-3 ( Indimitecan, LMP776)
	Name: Indotecan CAS#: 915303-09-2 Chemical Formula: C26H26N2O7 Exact Mass: 478.174 Molecular Weight: 478.49 Elemental Analysis: C, 65.26; H, 5.48; N, 5.85; O, 23.41
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: NSC-724998; NSC 724998; NSC724998; LMP400; LMP-400; LMP 400; Indotecan. Chemical Name: 2, 3-dimethoxy-6-(3-morpholinopropyl)-5H-[1, 3]dioxolo[4', 5':5, 6]indeno[1, 2-c]isoquinoline-5, 12(6H)-dione InChi Key: FMFIFGLHVOZDEL-UHFFFAOYSA-N InChi Code: InChI=1S/C26H26N2O7/c1-31-19-10-15-18(13-20(19)32-2)26(30)28(5-3-4-27-6-8-33-9-7-27)24-16-11-21-22(35-14-34-21)12-17(16)25(29)23(15)24/h10-13H, 3-9, 14H2, 1-2H3 SMILES Code: O=C1N(CCCN2CCOCC2)C3=C(C(C4=C3C=C(OCO5)C5=C4)=O)C6=C1C=C(OC)C(OC)=C6

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Amount: 50mg

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Delivery expected until 6/6/2024