msn125

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	250mg
Item no.	V6199-250mg
CASRN	1592908-16-1
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V6199CAS #:1592908-16-1Purity >=98% Description: MSN-125 is a novel and potent inhibitor of Bax and Bak oligomerization, which efficiently inhibits liposome permeabilization, preventing genotoxic cell death and promoting neuroprotection. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 uM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity. References: A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell?Chem Biol. 2017 Apr 20; 24(4):493-506.e5.

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Amount: 250mg

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Delivery expected until 6/6/2024