Comparison

Tanzisertib

Item no. MOLN-M22926-1g
Manufacturer Molnova
CASRN 899805-25-5
Amount 1 g
Quantity options 100 mg 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity >98% (HPLC)
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Molecular Weight
448, 44
Brief description
Tanzisertib (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.Tanzisertib (CC-930) inhibits the formation of phospho-cJun in human PBMC stimulated by phorbol-12-myristate-13-acetate and phytohemeagglutinin (IC50=1 μM)[1] and it blocks the JNK pathway that is activated by pro-fibrotic cytokines in systemic sclerosis.
Note
Research use only, not for human use.
Stability
≥ 2 years
Receptor
JNK3|JNK2|JNK1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 g
Available: In stock
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