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GDC0575 monohydrochloride

GDC0575 monohydrochloride

Item no.	MOLN-M27878-100mg
Manufacturer	Molnova
CASRN	1196504-54-7
Amount	100 mg
Quantity options	100 mg 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	>98% (HPLC)
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Molecular Weight	414, 73
Brief description	GDC-0575 is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
Note	Research use only, not for human use.
Stability	≥ 2 years
Receptor	hSGLT2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 9/11/2025

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