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Human MVK Protein (MVK-HB101)

Human MVK Protein (MVK-HB101)

Item no.	MVK-HB101-500UG
Manufacturer	KactusBio
Amount	500 ug
Quantity options	100 ug 500 ug
Category	Metabolism Cholesterol & Lipid Metabolism Peptides & Proteins Recombinant Proteins Enzymes Other Fatty Acid Enzymes
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	Insect Cells, Baculovirus-Infected Insect Cells
Conjugate/Tag	Strep, HIS, GST
Purity	> 90% as determined by Bis-Tris PAGE
Dry ice	Yes
Sequence	Met1-Leu396
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	MK,LRBP,POROK3,MVLK
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	MVK
Manufacturer - Conjugate / Tag	N-His-GST, C-Strep-II
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 72.23 kDa. The protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Description	Recombinant Human MVK Protein is expressed from Baculovirus-Insect Cells(Sf9) with His tag and GST tag at the N-terminus and Strep-II tag at the C-terminus.It contains Met1-Leu396.
Background	Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM NaCl, 2mM DTT, 10% glycerol (pH 7.4).
Biotinylated	no

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

MVK-HB101-500UG-datasheet.pdf

MVK-HB101-500UG-safety-datasheet.pdf