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Recombinant human PD-L1/B7-H1 protein (CD274)

Recombinant human PD-L1/B7-H1 protein (CD274)

Item no.	NKM-ATGP1543-250ug
Manufacturer	NKMAX
Amount	250 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 4 ug 500 ug 50 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Mesothelioma
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	<MGSSHHHHHH SSGLVPRGSH MGSHM>FTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEED LKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILV VDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRR LDPEENHTAE
Citations	Dong H., et al. (1999) Nat. Med. 5:1365-1369 Freeman G.J., et al. (2000) J. Exp. Med. 192:1027-1034
NCBI	NP_054862
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Programmed cell death 1 ligand,B7-H,B7H1,PD-L1,PDCD1L1,PDCD1LG1,PDL1
Similar products	B7H1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, B7-H, B7-H1, Programmed cell death 1 ligand, ATGP1543-10ug, ATGP1543-20ug, ATGP1543-50ug, ATGP1543-100ug, ATGP1543-250ug, ATGP1543-500ug, ATGP1543-1mg, ATGP1543-10, ATGP1543-20, ATGP1543-50, ATGP1543-100, ATGP1543-250, ATGP1543-500, ATGP1543-1
Available
Manufacturer - Type	Recombinant Protein
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	27.9 kDa (245aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Description	CD274, also known as programmed cell death 1 ligand 1 (PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interaction with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant human CD274 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Concentration	1mg/ml (determined by Bradford assay)
Formulation	Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT
Antigen Species	Human
Gene Category	Immunology
Domain	19-238aa
Species of Protein	Human
Manufacturer - Search Terms	PD-L1, B7-H1, Programmed cell death 1 ligand, B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, ATGP1543-10ug, ATGP1543-20ug, ATGP1543-50ug, ATGP1543-100ug, ATGP1543-250ug, ATGP1543-500ug, ATGP1543-1mg, ATGP1543-10, ATGP1543-20, ATGP1543-50, ATGP1543-100, ATGP1543-250, ATGP1543-500, ATGP1543-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 ug

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Delivery expected until 7/31/2025

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