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Recombinant human Beta-glucuronidase/GUSB protein

Recombinant human Beta-glucuronidase/GUSB protein

Item no.	NKM-ATGP3495-250ug
Manufacturer	NKMAX
Amount	250 ug
Quantity options	100 ug 10 ug 20 ug 250 ug 500 ug 50 ug 5 ug
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Necrosis
Type	Proteins Recombinant
Format	Liquid
Applications	SDS-PAGE
Specific against	Human (Homo sapiens)
Host	Baculovirus-Infected Insect Cells
Conjugate/Tag	HIS
Purity	> 90% by SDS-PAGE
Sequence	LQGGMLYPQE SPSRECKELD GLWSFRADFS DNRRRGFEEQ WYRRPLWESG PTVDMPVPSS FNDISQDWRL RHFVGWVWYE REVILPERWT QDLRTRVVLR IGSAHSYAIV WVNGVDTLEH EGGYLPFEAD ISNLVQVGPL PSRLRITIAI NNTLTPTTLP PGTIQYLTDT SKYPKGYFVQ NTYFDFFNYA GLQRSVLLYT TPTTYIDDIT VTTSVEQDSG LVNYQISVKG SN
Citations	Shipley JM., et al. (1993) Am J Hum Genet. 52:517-526. Bell CE Jr., et al. (1977) J Clin Invest. 59:97-105.
NCBI	NP_000172.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Beta-glucuronidase isoform 1,GUSB,BG,MPS7,Glucuronidase beta,Beta-G1
Similar products	GUSB, BG, MPS7, Beta-glucuronidase isoform 1, ATGP3495-10ug, ATGP3495-20ug, ATGP3495-50ug, ATGP3495-100ug, ATGP3495-250ug, ATGP3495-500ug, ATGP3495-1mg, ATGP3495-10, ATGP3495-20, ATGP3495-50, ATGP3495-100, ATGP3495-250, ATGP3495-500, ATGP3495-1
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Applications	SDS-PAGE, Enzyme Activity
Manufacturer - Host	Baculovirus
Storage Conditions	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight	73.4 kDa (635aa)
Description	GUSB, also known as beta-glucuronidase isoform 1, is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It includes heparin sulfate, chondroitin sulfate and hyaluronan. Mutations in the GUSB are linked to mucopolysaccharidosis type VII. GUSB plays an important role in the degradation of dermatan and keratin sulfates. Recombinant human GUSB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species	Human
Gene Category	Signal Transduction
Domain	23-651aa
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only	Specific activity is > 4000pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of 4-Methylum-belliferyl-beta-D-glucosiduronic acid to 4-Methylumbelliferone per minute at 37C and pH3.5.
Predicted nterm	Leu23
Species of Protein	Human
Manufacturer - Search Terms	GUSB, Beta-glucuronidase isoform 1, GUSB, BG, MPS7, ATGP3495-10ug, ATGP3495-20ug, ATGP3495-50ug, ATGP3495-100ug, ATGP3495-250ug, ATGP3495-500ug, ATGP3495-1mg, ATGP3495-10, ATGP3495-20, ATGP3495-50, ATGP3495-100, ATGP3495-250, ATGP3495-500, ATGP3495-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 ug

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Delivery expected until 9/4/2025

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