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[Novoprotein] Recombinant Human Cyclin-Dependent Kinase 2-Associated Protein 1/CXK2AP1 (C-6His)

[Novoprotein] Recombinant Human Cyclin-Dependent Kinase 2-Associated Protein 1/CXK2AP1 (C-6His)

Manufacturer	Bon Opus
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Hematology Lymphoma Peptides & Proteins Cell Biology Cell Status Proliferation Enzymes By Organ Bladder Cancer
Type	Proteins Recombinant
Specific against	Human
Format	Lyophilized
Amount	1mg
Host	Human
Item no.	C977-1mg
Targets	CDK2;;PCNA
Conjugate/Tag	His
eClass 6.1	34160400
eClass 9.0	42020190
Available
Background	Cyclin-Dependent Kinase 2-Associated Protein 1 (CDK2AP1) is a member of the CDK2AP family. The homodimeric structure of CDK2AP1 includes an intrinsically disordered 60-residue N-terminal region & a four-helix bundle dimeric structure with reduced Cys-105 in the C-terminal region. The widely expressed CDK2AP1 protein is the only known specific inhibitor of CDK2, making it an important component of cell cycle regulation during G(1)-to-S phase transition. In addition, CDK2AP1 serves as a regulatory role in DNA replication during S phase of the cell cycle.
Description	Recombinant Human CDK2AP1 is produced by our Mammalian expression system & the target gene encoding Met1-Ser115 is expressed with a 6His tag at the C-terminus.
Endotoxin	Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
Molecular Weight	13, 4
Reconstitution	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Seq Length	Met1-Ser115
Ship Description	The product is shipped at ambient temperature.
Storage	Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7C for 2-7 days. Aliquots of reconstituted samples are stable at < -20C for 3 months.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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