Background |
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain & liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, & neurodegenerative disorders. In addition, Clusterin is up/ down regulated on the mRNA or protein level in many pathological & clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity & others. |