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peptides & elephants

peptides & elephants

The peptides&elephants GmbH, based in Hennigsdorf, Brandenburg, has been producing peptides for international research since 2001. The company was founded by scientists from the German Institute of Human Nutrition in Potsdam and Charité in Berlin. Founder and owner Dr. Oliver J. Kreuzer personally develops the highly specialized synthesis robots of peptides & elephants, constantly setting new standards in peptide synthesis. With the development of the latest synthesis robot – the patented Ultra Sonic Peptide Synthesis (USPS®) platform – peptides & elephants has the ability to produce the required peptides at unprecedented speed and make them immediately available to researchers.

The peptides from peptides & elephants are primarily used in immunological research. They are used to understand the mechanisms behind cancer, infections, and autoimmune diseases in detail, and to develop new vaccines or immunotherapies against them.

Peptides from peptides & elephants are produced according to the strict quality guidelines of ISO 9001, ensuring the highest standards in production and safety. All peptides supplied by the company are guaranteed to be free from cross-contamination, enabling reliable and precise application in various research and development processes. Additionally, special capping steps ensure the sequence integrity of the peptides, guaranteeing their accuracy and reliability in scientific applications. Moreover, the peptides are sterile and endotoxin-free.

The reagents and solvents used for peptide synthesis are also Animal Component-Free (ACF) and Animal Origin-Free (AOF).

peptides & elephants offers a broad portfolio of catalog peptides and additionally synthesizes peptides, peptide pools, and peptide libraries on demand.

Peptid pools allow for comprehensive antigenic characterization of a protein in a single experimental approach. A peptide pool consists of a sequence of overlapping peptides that together represent a complete protein and are delivered in a single vial. For the synthesis, 15-mer peptide fragments are generated from the primary amino acid sequence, each overlapping by 11 amino acids. The 15-amino-acid length enables the individual epitopes of a peptide pool to bind both to MHC Class I and MHC Class II.

Peptide pools can be used for:

  • Antigen-specific stimulation in T-cell assays
  • Immune monitoring – Identification of T-cell epitopes
  • Mapping of T-cell epitopes
  • Development of cellular therapy and immunotherapy approaches
  • Vaccine development
  • Biological screening
  • Protein-protein interaction analyses

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