phaRNA

PhaRNA - Design and development of RNA constructs

PhaRNA LLC is a biotechnology company headquartered in Houston, Texas (USA). The company focuses on the design and production of in vitro transcribed (IVT) RNA constructs that encode messenger RNA (mRNA), long non-coding RNA (lncRNA) and other RNA species 150 nucleotides or longer. PhaRNA was founded by scientists with a long history of innovation and combines their broad know-how to improve the design and production of RNA for basic and translational research including preclinical, clinical, cosmetic and veterinary applications.

The advantages of using RNA in research and therapy are based on the properties of ribonucleic acid. After insertion, the RNA does not have to be introduced into the nucleus, but can be translated directly in the cytoplasm. The desired effects are dose-dependent and have a low toxicity with high viability. Our partner PhaRNA supplies the appropriate transfection protocol for most cell types. Compared to DNA, RNA often has a greater transfection efficiency.

The proprietary technology of our partner guarantees the generation of highly stable and efficiently translatable RNA species. PhaRNA aims to provide high quality long ribonucleic acid generation services to the scientific and medical community. State-of-the-art research and development laboratories enable the provision of first-class RNA products for efficacy and toxicity studies.

PhaRNA has the world's largest archive of messenger RNA mimetics (mRNA mimetics) for research and development activities. These are natural mRNA analogs or transcripts with mmRNA (modified messenger RNA). PhaRNA is also specialized in the design and synthesis of fusion and/or bi-/polycistronic mRNA-mimetic constructs, as well as long non-coding RNA (lncRNA) products.

In addition to an extensive product catalog, PhaRNA LLC offers customized synthesis. In principle, this can be used for every gen of interest, size and complexity are not an issue. One example are fusion proteins that consist of the fluorescently labeled target gene. Another service of the company includes the differentiation of embryonic stem cells and iPSCs into different cell types and mRNA-based reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). PhaRNA is prepared for specific concerns of any kind.

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PhaRNA products by Product Category

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  Nucleic Acids
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PhaRNA products by Research Area

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  Cell Biology
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  Metabolism
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  Neuroscience
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  Oncology