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Partner: ProteoGenix | Hölzel Diagnostika

ProteoGenix

Proteogenix

ProteoGenix – Outstanding Antibodies and Recombinant Proteins

The French company ProteoGenix has been developing and manufacturing diagnostic tests and biotherapeutics since its establishment in 2003. Until now, our partner has established as one of the world's leading antibody producers who impress with their first-class performance. The secret of success lies in extensive know-how and most modern technologies paired with daily commitment for the success of your projects.

A team of highly qualified and committed experts assists customers in the production of antibodies. Customers are supported when generating monoclonal antibodies through hybridoma development or through phage display up to bioproduction. The services are 100% customizable and include engineering options such as antibody humanization, affinity maturation, etc. Our partner has more than 15 years of experience in the production of high-quality monoclonal antibodies. Thereby ProteoGenix offers a complete, one-stop solution, from antigen design to the delivery of purified polyclonal antibodies.

ProteoGenix extensive services also include protein expression and purification on a laboratory and industrial scale. The service includes all steps from gene synthesis and construction of the expression vector to pilot production in culture flasks and protein expression in fermenters and bioreactors. As protein expression system you can choose between E. coli, B. subtilis, yeast, insect cells or mammalian cells, or test in several systems in parallel or extended protein expression conditions in a specific system. The ProteoGenix high throughput screening of protein expression conditions is designed to overcome problems related to solubility, purity, function, productivity, refolding, or formulation. Keeping the promise of high quality standards requires availability and mastery of all existing technologies, processes and tools. Based on extensive experience in the expression of recombinant proteins of any kind such as antibodies, enzymes, membrane proteins, cytokines etc. and a wide variety of species, ProteoGenix has developed a complete set of tools for all challenges, in order to offer first-class protein engineering services that meet every challenge can master in this area.

Our partner ProteoGenix offers productivity of up to 800 mg/l with transient expression and 5 g/l with stable expression. While operating as a Contract Research Organization (CRO), ProteoGenix has leveraged its cutting-edge technologies and years of experience in protein and antibody production to develop unique reagents:

Monoclonal polyclonal antibodies (7 types available: rabbit, chicken, mouse, rat, guinea pig, sheep, goat antiserum and more) that bind specific antigens
Difficult to express recombinant proteins in five systems (E. coli, B. subtilis, yeast (P. pastoris and S. cerevisiae), insect cells and mammalian cells)