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Recombinant Human MeCP2 protein(His tag)

Recombinant Human MeCP2 protein(His tag)

Item no.	PDEH100777-500ug
Manufacturer	Elabscience
Amount	500 ug
Quantity options	100 ug 1 mg 20 ug 500 ug
Format	Lyophilized Powder
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS
Purity	> 95% as determined by reducing SDS-PAGE.
Sequence	Met1-Lys177
Alias	MeCp-2 protein
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	19.0 kDa
Observed Molecular Weight	32 kDa
Manufacturer - Research Areas	Epigenetics and Nuclear Signaling, Neuroscience
Background	Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Abbreviation	MeCP2
Endotoxin	< 10 EU/mg of the protein as determined by the LAL method.
Reconstitution	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

PDEH100777-500ug-datasheet.pdf

PDEH100777-500ug-safety-datasheet.pdf