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Recombinant Human ATXN2 protein (GST tag)

Recombinant Human ATXN2 protein (GST tag)

Item no.	PDEH100783-20ug
Manufacturer	Elabscience
Amount	20 ug
Quantity options	100 ug 1 mg 20 ug 500 ug
Format	Lyophilized Powder
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	GST
Purity	> 95% as determined by reducing SDS-PAGE.
Sequence	Leu 460-Ser 600
Alias	ATX2, ATXN2, Ataxin-2, SCA2, Spinocerebellar ataxia type 2 protein, TNRC13, Trinucleotide repeat-containing gene 13 protein
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	N-GST
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	40.4 kDa
Observed Molecular Weight	42 kDa
Manufacturer - Research Areas	Epigenetics and Nuclear Signaling
Background	Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.
Abbreviation	ATXN2
Endotoxin	< 10 EU/mg of the protein as determined by the LAL method.
Reconstitution	It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Not validated for activity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

PDEH100783-20ug-datasheet.pdf

PDEH100783-20ug-safety-datasheet.pdf