Comparison

CYP27B1 Antibody (C-term) Blocking peptide

Item no. ABC-BP12284b
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products CYP27B1, mitochondrial, CYP1ALPHA, CYP27B, 25-hydroxyvitamin D-1 alpha hydroxylase, 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, Calcidiol 1-monooxygenase, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, VD3 1A hydroxylase, Cytochrome p450 27B1, Cytochrome P450VD1-alpha
Available
Primary Accession
O15528
Bio Background
This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.The protein encoded by this gene localizes to the innermitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3at the 1alpha position. This reaction synthesizes1alpha, 25-dihydroxyvitamin D3, the active form of vitamin D3, whichbinds to the vitamin D receptor and regulates calcium metabolism.Thus this enzyme regulates the level of biologically active vitaminD and plays an important role in calcium homeostasis. Mutations inthis gene can result in vitamin D-dependent rickets type I.
Bio References
Giroux, S., et al. Bone 47(5):975-981(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Holt, S.K., et al. Prostate 70(13):1448-1460(2010)Alzahrani, A.S., et al. J. Clin. Endocrinol. Metab. 95(9):4176-4183(2010)Sundqvist, E., et al. Eur. J. Hum. Genet. (2010) In press :
Gene ID
1594
Gene Name
CYP27B1
Subtitle
Synthetic peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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