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Phospho-STAT6-Y641 Antibody Blocking Peptide

Phospho-STAT6-Y641 Antibody Blocking Peptide

Manufacturer	Abcepta
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Amount	500 ug
Item no.	ABC-BP3270a
eClass 6.1	34160400
eClass 9.0	32160409
Available
Primary Accession	P42226
Bio Background	STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.
Bio References	Valineva, T., et al., J. Biol. Chem. 280(15):14989-14996 (2005).Tang, X., et al., Proc. Natl. Acad. Sci. U.S.A. 102(14):5132-5137 (2005).Heller, N.M., et al., Am. J. Respir. Cell Mol. Biol. 31(5):573-582 (2004).Galka, E., et al., J. Surg. Res. 122(1):14-20 (2004).Zhang, W.J., et al., Int. J. Oncol. 24(2):447-453 (2004).
Gene ID	6778
Gene Name	STAT6
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP3270a was selected from the region of human Phospho-STAT6-Y641. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP3270a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 7/4/2024