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GSK3 beta (GSK3B) Antibody (C-term) Blocking peptide

GSK3 beta (GSK3B) Antibody (C-term) Blocking peptide

Item no.	ABC-BP8121b
Manufacturer	Abcepta
Amount	500 ug
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Dajani, R., et al., Cell 105(6):721-732 (2001).Lau, K.F., et al., Genomics 60(2):121-128 (1999).Rhoads, A.R., et al., Mol. Psychiatry 4(5):437-442 (1999).Delcommenne, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(19):11211-11216 (1998).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Glycogen synthase kinase-3 beta,GSK-3 beta,Serine/threonine-protein kinase GSK3B,GSK3B
Similar products	GSK3B, Glycogen synthase kinase-3 beta, Serine/threonine-protein kinase GSK3B, GSK-3 beta
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP8121b was selected from the C-term region of human GSK3B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
Gene Name	GSK3B
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP8121b-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 11/6/2025

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