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Spike protein (S2) SARS-CoV-2 substrate - 0.1 mg

Spike protein (S2) SARS-CoV-2 substrate - 0.1 mg

Item no.	AS-65601
Manufacturer	AnaSpec
Amount	0.1 mg
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Purity	Peak Area by HPLC ≥95%
Sequence	QXL®520-Ser-Lys-Pro-Ser-Lys-Arg-Ser-Phe-Ile-Glu-Asp-Lys(5-FAM)-OH
Citations	Coutard B, et al. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Res. 2020 Apr;176:104742. doi: 10.1016/j.antiviral.2020.104742.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	QXL520-SKPSKRSFIED-K(5-FAM)-NH2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Catalog
Manufacturer - Applications	FRET; Screening; Protease activity; Receptor binding studies
Manufacturer - Category	Peptides
Manufacturer - Targets	Furin; Spike protein
Manufacturer - Conjugate / Tag	FAM-QXL® 520
Shipping Temperature	RT
Storage Conditions	- 20 °C Protected from light
Molecular Weight	2270.4
Description	This peptide sequence represents a second furin-like cleavage site of the Spike (S) protein also thought to participate in the process of viral entry into host cell. The sequence at the S2 site (KR?SF) contains two basic residues (P1 and P2) and a hydrophobic P3 residue. This site is identical between the SARS-CoV-2 and SARS-CoV. This peptide has been labeled with QXL520 and 5-FAM.
Product Group	LB1A1Z
Research Area	Cell Signaling; Immunology and Infectious disease / Lyophilized
Absorbtion (nm)	490
Emission (nm)	520
Sequence One-Letter Code	QXL®520-SKPSKRSFIED-K(5-FAM)-NH2
GTIN	5400535177409
Detection Method	Fluorescent
Usage	Research use
UNSPSC	12352202

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AS-65601-safety-datasheet.pdf