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HPK1-IN-21

HPK1-IN-21

Item no.	HY-144073-1ea
Manufacturer	MedChem Express
CASRN	2413804-83-6
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Formula	C22H25ClFN5O2
Citations	[1]Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1). ACS Med Chem Lett. 2021, 13(1):84-91.
Smiles	CN(C(C1=C(C(C2=C(C3=C(NC[C@@]34CC[C@](C(N)=O)(C4)C)N=C2)Cl)=CC=C1N)F)=O)C
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	MAP4K
Shipping Temperature	Room Temperature
Molecular Weight	445.92
Product Description	HPK1-IN-21 is a potent inhibitor of HPK1 kinase inhibitor (Ki=0.8 nM). HPK1-IN-21 also has orally active[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	MAPK/ERK Pathway
Isoform	MAP4K1/HPK1
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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